Scientific References

The FemiPro formula is backed by clinical studies and scientific research related to the urinary microbiome and botanical efficacy. Below are the peer-reviewed sources supporting our approach:

1. Carnes MU, Siddiqui NY, Karstens L, Gantz MG, et al. Urinary microbiome community types associated with urinary incontinence severity in women. American Journal of Obstetrics and Gynecology. 2024 Mar 1;230(3):344-e1.
2. Diaz A. “Call a F–king lawyer”: TikTokers issue dire warning over common tampon ingredient [Internet]. New York Post; 2022.
3. Govender Y, Gabriel I, Minassian V, Fichorova R. The Current Evidence on the Association Between the Urinary Microbiome and Urinary Incontinence in Women. Frontiers in Cellular and Infection Microbiology. 2019 May 1.
4. Heid M. The Truth About Your Tampons [Internet]. Time; 2016.
5. Komesu YM, Richter HE, Carper B, et al. The urinary microbiome in women with mixed urinary incontinence compared to similarly aged controls. International Urogynecology Journal. 2018 Dec.
6. Mandal AK, Pandey A, Sah RK, et al. In Vitro Antioxidant and Antimicrobial Potency of Mimosa pudica of Nepalese Terai Region: Insight into L-Mimosine as an Antibacterial Agent. Evidence-Based Complementary and Alternative Medicine. 2022.
7. Mei Z, Li D. The role of probiotics in vaginal health. Frontiers in Cellular and Infection Microbiology. 2022 Jul 28.
8. Meštrović Popovič K, Povalej Bržan P, Langerholc T, Marčun Varda N. The Impact of Lactobacillus Plantarum PCS26 Supplementation on the Treatment and Recurrence of Urinary Tract Infections in Children-A Pilot Study. Journal of Clinical Medicine. 2022.
9. Molina MA, Melchers WJ, Núñez-Samudio V, Landires I. The emerging role of Lactobacillus acidophilus in the cervicovaginal microenvironment. The Lancet Microbe. 2024 Jan 1.
10. Paniágua AL, Correia AF, Pereira LC, et al. Inhibitory effects of Lactobacillus casei Shirota against both Candida auris and Candida spp. isolates that cause vulvovaginal candidiasis and are resistant to antifungals. BMC Complementary Medicine and Therapies. 2021.
11. Petriello MC, Hoffman JB, Vsevolozhskaya O, Morris AJ, Hennig B. Dioxin-like PCB 126 increases intestinal inflammation and disrupts gut microbiota and metabolic homeostasis. Environmental Pollution. 2018 Nov.
12. Pino A, Rapisarda AM, Vitale SG, et al. A clinical pilot study on the effect of the probiotic Lacticaseibacillus rhamnosus TOM 22.8 strain in women with vaginal dysbiosis. Scientific Reports. 2021 Jan 28.
13. Price TK, Lin H, Gao X, et al. Bladder bacterial diversity differs in continent and incontinent women: a cross-sectional study. American Journal of Obstetrics and Gynecology. 2020 Nov.
14. Redondo-Lopez V, Cook RL, Sobel JD. Emerging role of lactobacilli in the control and maintenance of the vaginal bacterial microflora. Reviews of infectious diseases. 1990.
15. Ren LM, Zhuo YJ, Hao ZS, et al. Berberine improves neurogenic contractile response of bladder detrusor muscle in streptozotocin-induced diabetic rats. Journal of Ethnopharmacology. 2013 Dec 12.
16. Reuters. FDA warns J&J unit about tampon complaints [Internet]. Reuters; 2012.
17. Sousa LGV, Pereira SA, Cerca N. Fighting polymicrobial biofilms in bacterial vaginosis. Microbial Biotechnology. 2023 Jul.
18. Sobota AE. Inhibition of bacterial adherence by cranberry juice: potential use for the treatment of urinary tract infections. The Journal of Urology. 1984 May 1.
19. Thomas-White K, Vo C. How Lactobacillus Gasseri Can Support Your Vaginal Health [Internet]. Evvy. 2024.
20. Tóth B, Jávorházy A, Nyirády P, et al. Bearberry in the treatment of acute uncomplicated cystitis (BRUMI): protocol of a multicentre, randomised double-blind clinical trial. BMJ Open. 2022 Jun 24.
21. Tsiaoussis J, Antoniou MN, Koliarakis I, et al. Effects of single and combined toxic exposures on the gut microbiome: Current knowledge and future directions. Toxicology letters. 2019 Sep 15.
22. Wolfe AJ, Brubaker L. Urobiome updates: advances in urinary microbiome research. Nature Reviews Urology. 2019 Feb.
23. World Health Organization. Dioxins [Internet]. World Health Organization; 2023.
24. Wu P, Chen Y, Zhao J, et al. Urinary microbiome and psychological factors in women with overactive bladder. Frontiers in cellular and infection microbiology. 2017 Nov 27.